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Development of transgenic avian bioreactor systems for the production of recombinant proteins 2010.08.12

[Engineering]
Masamichi Kamihira(Professor)Staff information
Akira Ito(Associate Professor)Staff information
Yoshinori Kawabe(Assistant Professor)Staff information
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[ 研究概要 ] Biopharmaceuticals such as monoclonal antibodies and erythropoietin have been produced mainly by recombinant animal cell cultures. However, the production cost in animal cell cultures is very high even though genetic engineering and culture technology have well developed. In recent years, transgenic bioreactors have been proposed as a novel production system for biopharmaceutical proteins. We have developed various techniques to generate transgenic avian species for the production of biopharmaceuticals into eggs, and we have attempted to produce recombinant proteins using transgenic avian bioreactors. [ Related Key Word ] transgenic avian | biopharmaceuticals | transgenic bioreactor | viral vector

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